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Research on Journal Covers

  Cornell Publications

Note: For interested readers, the Supplementary Materials to our publications are as important as the main papers.

(46) J. B. Sambur, P. Chen
“Approaches to Single-Nanoparticle Catalysis”
 Annual Review of Physical Chemistry, 2014, 65, 395-422. [pdf]
 
(45) P. Chen, X. Zhou, N. M. Andoy, K.-S. Han, E. Choudhary, N. Zou, G. Chen, H. Shen
“Spatiotemporal Catalytic Dynamics within Single Nanocatalysts Revealed by Single-Molecule Microscopy”
Chemical Society Reviews 2014, 43, 1107-1117. [pdf]
Invited contribution to the themed issue “Single-molecule optical spectroscopy”.
(44) P. Chen, A. M. Keller, C. P. Joshi, D. J. Martell, N. M. Andoy, J. J. Benítez, T.-Y. Chen, A. G. Santiago, F. Yang
“Single-Molecule Dynamics and Mechanisms of Metalloregulators and Metallochaperones”
Biochemistry 2013, 52, 7170-7183. [pdf]
Invited Current Topic article.
 
(43) M. A. Ochoa, P. Chen, R. F. Loring
“Single turnover measurements of nanoparticle catalysis analyzed with dwell time correlation functions and constrained mean dwell times”
Journal of Physical Chemistry C 2013117, 19074-19081. [pdf]
 
(42) X. Zhou, E. Choudhary, N. M. Andoy, N. Zou, P. Chen
“Scalable Parallel Screening of Catalyst Activity at the Single-Particle Level and Sub-diffraction Resolution”
ACS Catalysis 2013, 3, 1448-1453. [pdf] [Supp Info]

News highlight: "Imaging method identifies most active catalyst particles" by Mitch Jacoby, Chemical & Engineering News, 2013, 91, 31.

 
(41) N. M. Andoy, X. Zhou, E. Choudary, H. Shen, P. Chen
"Single-Molecule Catalysis Mapping Quantifies Site-specific Activity and Uncovers Radial Activity Gradient on Single 2D Nanocrystals"
Journal of the American Chemical Society, 2013, 135, 1845-1852. [pdf] [Supp Info]
 
(40) C. P. Joshi, D. Panda, D. J. Martell, N. M. Andoy, T.-Y. Chen, A. Gaballa, J. D. Helmann, P. Chen
"Direct Substitution and Assisted Dissociation Pathways for Turning Off Transcription by A MerR-family Metalloregulator"
Proceedings of the National Academy of Sciences of the U.S.A., 2012, 109, 15121-15126. [pdf] [Supp Info]
Equal contribution.

News highlight: "Proteins barge in to turn off unneeded genes and save energy" by Bill Steele, Cornell Chronicle, September 5, 2012.

 
(39) A. M. Keller, J. J. Benitez, D. Klarin, L. Zhong, M. Goldfogel, F. Yang, T.-Y. Chen, P. Chen
"Dynamic Multi-Body Protein Interactions Suggest Versatile Pathways for Copper Trafficking"
Journal of the American Chemical Society, 2012, 134, 8934-8943. [pdf] [Supp Info]
TOC graph
   
(38) Y.-F. Chen, X. Serey, R. Sarkar, P. Chen, D. Erickson

"Controlled photonic manipulation of proteins and other nanomaterials"

Nano Letters, 2012, 12, 1633-1637. [pdf]

   
(37) K.-S. Han, G. Liu, X. Zhou, R. E. Medina, P. Chen

"How does A Single Pt Nanocatalyst Behave in Two Different Reactions? A Single-Molecule Study"

Nano Letters, 2012, 12, 1253-1259. [pdf] [Supp Info]

Equal contribution.

   
(36) X. Zhou, N. M. Andoy, G. Liu, E. Choudhary, K.-S. Han, H. Shen, P. Chen

"Quantitative Super-resolution Imaging Uncovers Reactivity Patterns on Single Nanocatalysts"

Nature Nanotechnology, 2012, 7, 237–241. [pdf] [Supp Info]

News highlights:

   
(35) P. Chen

"Solid Acid Catalysts: Stain and Shine"

Nature Chemistry, 2011, 3, 839-840. [pdf]

Invited News and Views article.

   
(34) M. A. Ochoa-Daza, X. Zhou, P. Chen, R. F. Loring

"Interpreting Single Turnover Catalysis Measurements with Constrained Mean Dwell Times"

Journal of Chemical Physics, 2011, 135, 174509. [pdf]

   
(33)

J. J. Benitez, A. M. Keller, D. L. Huffman, L. Yatsunyk, A. C. Rosenzweig, P. Chen

"Relating Dynamic Protein Interactions of Metallochaperones with Metal Transfer at the Single-Molecule Level"

Faraday Discussions, 2011, 148, 71-82. [pdf]

Invited contribution to the special volume: Spectroscopy, Theory and Mechanism in Bioinorganic Chemistry.

   
(32)

P. Chen, X. Zhou, H. Shen, N. M. Andoy, E. Choudhary, K.-S. Han, G. Liu, W. Meng

"Single-Molecule Fluorescence Imaging of Nanocatalytic Processes"

Chemical Society Reviews, 2010, 39, 4560-4570. [pdf]

Invited Tutorial Review to the themed issue: In-situ characterization of heterogeneous catalysts.

   
(31)

H. Shen, W. Xu, P. Chen

"Single-Molecule Nanoscale Electrocatalysis"

Physical Chemistry Chemical Physics, 2010, 12, 6555-6563. [pdf]

Invited Perspective article.

   
(30)

P. Chen, N. M. Andoy, J. J. Benitez, A. M. Keller, D. Panda, F. Gao

"Tackling Metal Regulation and Transport at the Single-Molecule Level"

Natural Product Reports, 2010, 27, 757-767. [pdf]

Invited review to the thematic issue of Metals in Cells.

   
(29)

J. J. Benitez, A. M. Keller, P. Chen

"Nanovesicle Trapping for Studying Weak Protein Interactions by Single-Molecule FRET"

Methods in Enzymology, 2010, 472, 41-60. [pdf]

Invited article to the special volume of Single Molecule Tools: Fluorescence Based Approaches.

   
(28)

X. Zhou, W. Xu, G. Liu, D. Panda, P. Chen

"Size Dependent Catalytic Activity and Dynamics of Gold Nanoparticles at the Single-Molecule Level"

Journal of the American Chemical Society, 2010, 132, 138-146. [pdf] [Supp Info]

   
(27)

W. Xu, H. Shen, G. Liu, P. Chen

"Single-Molecule Kinetics of Nanoparticle Catalysis"

Nano Research, 2009, 2, 911-922. [pdf]

Invited review article.

   
(26)

N. M. Andoy, S. K. Sarkar, Q. Wang, D. Panda, J. J. Benitez, A. Kalininskiy, P. Chen

"Single-Molecule Study of Metalloregulator CueR-DNA Interactions Using Engineered Holliday Junctions"

Biophysical Journal 2009, 97, 844-852. [pdf] [Supp Info]

Featured on the journal cover.

   
(25)

W. Xu, H. Shen, Y. J. Kim, X. Zhou, G. Liu, J. Park, P. Chen

"Single-Molecule Electrocatalysis by Single-Walled Carbon Nanotubes"

Nano Letters, 2009, 9, 3968–3973. [pdf] [Supp Info]

Featured on the journal cover.

 

News highlights:

 

   
(24)

P. Chen, W. Xu, X. Zhou, D. Panda, A. Kalininskiy

"Single-Nanoparticle Catalysis at Single-Turnover Resolution"

Chemical Physics Letters 2009, 470, 151-157. [pdf]

Invited FRONTIERS article. Featured on the journal cover.

   
(23)

W. Xu, J. S. Kong, P. Chen

"Probing the Catalytic Activity and Heterogeneity of Au-Nanoparticles at the Single-Molecule Level"

Physical Chemistry Chemical Physics 2009, 11, 2767-2778. [pdf]

 

News highlights:

   
(22)

W. Xu, J. S. Kong, P. Chen

"Single-Molecule Kinetic Theory of Heterogeneous and Enzyme Catalysis"

Journal of Physical Chemistry C, 2009, 113, 2393-2404. [pdf]

 

   
(21)

P. Chen, N. M. Andoy

"Single-Molecule Fluorescence Methods in Enzymology"

In Comprehensive Natural Products Chemistry II Chemistry and Biology; Mander, L., Lui, H.-W., Eds.; Elsevier: Oxford, 2010; Vol. 9; pp 751. [pdf]
Invited review.

   
(20)

W. Xu, J. S. Kong, Y.-T. E. Yeh, P. Chen

"Single-Molecule Nanocatalysis Reveals Heterogeneous Reaction Pathways and Catalytic Dynamics"

Nature Materials 2008, 7, 992-996. [pdf] [Supp Info]

 

News highlights:

 

 

(19)

J. J. Benítez, A. M. Keller, P. Ochieng, L. A. Yatsunyk, D. L. Huffman, A. C. Rosenzweig, P. Chen

"Probing Transient Copper Chaperone-Wilson Disease Protein Interactions at the Single-Molecule Level with Nanovesicle Trapping"

Journal of the American Chemical Society 2008, 130, 2446-2447. [pdf] [Supp Info] [Supp Info 2]

Correction/Addition: J. Am. Chem. Soc. 2009, 131, 871.

 

 
(18)

P. Chen, N. M. Andoy

"Single-Molecule Fluorescence Studies from A Bioinorganic Perspective"

Inorganica Chimica Acta 2008, 361, 809-819. [pdf]

Invited contribution to the special issue in honor of Edward I. Solomon.

 
 
(17)

S. K. Sarkar, N. M. Andoy, J. J. Benítez, P. R. Chen, J. S. Kong, C. He, P. Chen

"Engineered Holliday Junctions as Single-Molecule Reporters for Protein-DNA Interactions with Application to a MerR-Family Regulator"

Journal of the American Chemical Society 2007, 129, 12461-12467. [pdf] [Supp Info]

 
 
 
  Postdoctoral and Graduate Publications
(16) Nan, X.; Sims, P. A.; Chen, P.; Xie, X. S. "Observation of Individual Microtubule Motor Steps in Living Cells with Endocytosed Quantum Dots" J. Phys. Chem. B 2005, 109, 24220-24224. [pdf]

Press highlight: "Motor steps imaged in living cells", Chemical & Engineering News, January 2, 2006, Volume 84, p22.
 
(15) Solomon, E. I.; Basumallick, L.; Chen, P.; Kennepohl, P. "Variable Energy Photoelectron Spectroscopy: Electronic Structure and Electronic Relaxation"  Coord. Chem. Rev. (Invited Issue of Synchrotron Radiation in Inorganic and Bioinorganic Chemistry), 2005, 249, 229-253. [pdf]
 
(14) Chen, P.; Solomon, E. I., "O2 Activation by Binuclear Cu Sites: Non-Coupled versus Exchange Coupled Reaction Mechanisms" Proc. Natl. Acad. Sci. USA 2004, 101, 13105-13110. [pdf]
 
(13) Chen, P.; Gorelsky, S. I.; Ghosh, S.; Solomon, E. I. "N2O Reduction by the m4-Sulfide Bridged Tetranuclear CuZ Cluster Active Site" Angew. Chem. Int. Ed. 2004, 43, 4132-4140. [pdf]
 
(12) Chen, P.; Solomon, E. I., "Oxygen Activation by the Non-Coupled Binuclear Copper Site in Peptidylglycine a-Hydroxylating Monooxygenase. Reaction Mechanism and Role of the Non-Coupled Nature of the Active Site" J. Am. Chem. Soc. 2004, 126, 4991-5000. [pdf]
 
(11) Chen, P.; Bell, P.; Eipper, B. A.; Solomon, E. I. "Oxygen Activation by the Non-Coupled Binuclear Copper Site in Peptidylglycine a-Hydroxylating Monooxygenase. Spectroscopic Definition of the Resting Sites and the Putative CuIIM-OOH Intermediate" Biochemistry 2004, 43, 5735-5747. [pdf]
 
(10) Ghosh, S.; Gorelsky, S. I.; Chen, P.; Cabrito, I.; Moura, J. J. G.; Moura, I.; Solomon, E. I. "Activation of N2O Reduction by the Fully Reduced m4-Sulfide Bridged Tetranuclear CuZ Cluster in Nitrous Oxide Reductase" J. Am. Chem. Soc. 2003, 125, 15708-15709. [pdf]
 
(09) Chen, P.; Fujisawa, K.; Helton, M. E.; Karlin, K. D.; Solomon, E. I. "Spectroscopy and Bonding in Side-On and End-On Cu2(S2) Cores: Comparison to Peroxide Analogues" J. Am. Chem. Soc. 2003, 125, 6394-6408. [pdf]
 
(08) Helton, M. E.; Chen, P.; Paul, P. P.; Tyeklár, Z.; Sommer, R.; Zhakarov, L.; Rheingold, A. L.; Solomon, E. I.; Karlin, K. D. "Reaction of Elemental Sulfur with a Copper(I) Complex Forming a trans-m-1,2 End-On Disulfide Complex: New Directions in Copper-Sulfide Chemistry" J. Am. Chem. Soc. 2003, 125, 1160-1161. [pdf]
 
(07) Chen, P.; Root, D. E.; Campochiaro, C.; Fujisawa, K.; Solomon, E. I. "Spectroscopic and Electronic Structure Studies of the Diamagnetic Side-On CuII-Superoxo Complex Cu(O2)[HB(3-R-5-iPrpz)3]: Antiferromagnetic Coupling versus Covalent Delocalization" J. Am. Chem. Soc. 2003, 125, 466-474. [pdf]
 
(06) Chen, P.; Cabrito, I.; Moura, J. J. G.; Moura, I.; Solomon, E. I. "Spectroscopic and Electronic Structure Studies of the m4-Sulfide Bridged Tetranuclear CuZ Cluster in N2O Reductase: Molecular Insight into the Catalytic Mechanism" J. Am. Chem. Soc. 2002, 124, 10497-10507. [pdf]
 
(05) Chen, P.; George, S. D.; Cabrito, I.; Antholine, W. E.; Moura, J. J. G.; Moura, I.; Hedman, B.; Hodgson, K. E.; Solomon, E. I. "Electronic Structure Description of the m4-Sulfide Bridged Tetranuclear CuZ Center in N2O Reductase" J. Am. Chem. Soc. 2002, 124, 744-745. [pdf]
 
(04) Chen, P.; Solomon, E. I. "Frontier Molecular Orbital Analysis of Cun-O2 Reactivity" J. Inorg. Biochem. (Invited 30th Anniversary Issue) 2002, 88, 368-374. [pdf]
 
(03) Chen, P.; Cabrito, I.; Antholine, W. E.; Moura, I.; Moura, J. J. G.; Solomon, E. I. "Spectroscopic Studies of the CuZ Center of Nitrous Oxide Reductase" J. Inorg. Biochem. (ICBIC10 Issue) 2001, 86, 177.
 
(02) Solomon, E. I.; Chen, P.; Metz, M.; Lee, S. K., Palmer, A. E. "Oxygen Binding, Activation and Reduction to Water by Copper Proteins" Angew. Chem. Int. Ed. 2001, 40, 4570-4590; Angew. Chem. 2001, 113, 4702-4724. [pdf]
 
(01) Chen, P.; Fujisawa, K.; Solomon, E. I. "Spectroscopic and Theoretical Studies of Mononuclear Copper(II) Alkyl- and Hydroperoxo Complexes: Electronic Structure Contributions to Reactivity" J. Am. Chem. Soc. 2000, 122, 10177-10193. [pdf]